Atracurium in anaesthetized man.
نویسنده
چکیده
Bortoluzzi, E., Roella, C , Bortoluzzi, S. L., and Montoli, E. (1963). Methylphenidate in the treatment of shivering. Anesth. Analg. (Clcvc), 42, 325. Brichard, G., and Johnstone, M. (1970). The effect of methylphenidate (Ritalin) on post-halothane muscle spasticity. Br. J. Anaesth., 42, 718. Maxwell, R. A., Sylwestrowicz, H. D., Holland, R., Schneider, F., and Daniel, A. I. (1961). Some actions of methylphenidate on the vascular system, arterial tissue and the nictitating membrane. J. Pharmacol. Exp. Ther., 131, 355.
منابع مشابه
The pharmacology of atracurium: a new competitive neuromuscular blocking agent.
Atracurium besylate, 2,2'-(3,11-dioxo-4,10-dioxatridecylene)-bis-[6,7-dimethoxy-1-(3,4-dimethoxy-benzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolinium] dibenzenesulphonate, is one of a new series of competitive neuromuscular blocking agents. An i.v. dose of 0.25 mg kg-1 produced complete paralysis in anaesthetized cats, dogs and rhesus monkeys; paralysis was of medium duration and was readily antag...
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Among the non-depolarizing neuromuscular blocking drugs, atracurium appears to be unique in its ability to produce cerebral stimulation in lightly anaesthetized animals. This effect is attributed to the atracurium metabolite, laudanosine. The following studies were performed to determine if pretreatments with the non-depolarizing neuromuscular blockers pancuronium, atracurium or vecuronium woul...
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The effects of vecuronium and atracurium on neuromuscular transmission, on the responses of the heart rate to vagal stimulation and on the responses to preganglionic stimulation of the nictitating membrane were compared in the chloralose-anaesthetized cat. Vecuronium was four times more potent than atracurium as a neuromuscular blocking agent, whereas the two compounds had similar potencies in ...
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We have defined the pharmacokinetics of atracurium besylate 0.25 mg kg-1 in 41 patients anaesthetized with 0.9% isoflurane end-tidal, 0.5% halothane end-tidal or midazolam 3-10 mg as a supplement to 66% nitrous oxide in oxygen. The pharmacokinetic profile was affected by age, sex and anaesthetic technique. Advancing age was associated with a reduced clearance and a longer elimination half-time;...
متن کاملHistamine release during the administration of atracurium or vecuronium in children.
The histamine releasing potential of equivalent bolus doses of atracurium 0.6 mg kg-1 or vecuronium 0.12 mg kg-1 was evaluated in 20 children anaesthetized with halothane. Blood samples were obtained before, and at 2 and 5 min after the administration of the neuromuscular blocker. The twitch response to 0.15 Hz was also evaluated. None of the 10 patients receiving vecuronium had a significant i...
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ورودعنوان ژورنال:
- British journal of anaesthesia
دوره 53 12 شماره
صفحات -
تاریخ انتشار 1981